A variety of drugs are needed to treat different cancers. Drugs which work well for some cancers or patients may not work well for others. To address this problem, Endocyte is developing a portfolio of targeted drugs to provide the most effective therapy for each cancer type.

Our initial focus is on folate-receptor-targeted therapies for treatment of cancer. Folate is required for cell division and rapidly dividing cancers up-regulate receptors for folate. We are also developing targeted therapies for other cancer-cell receptors and other diseases.

An essential part of our strategy is the use of companion diagnostic imaging agents like EC20 and EC0652 to predict whether the drug will reach the sites of disease (see predictive medicine).