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A major problem with many drug therapies is the inability to predict patient response. New predictive medicine tools, such as companion diagnostic imaging, are needed to identify how well a patient will respond to a particular drug therapy.
Recognizing this critical need for new predictive medicine tools, Endocyte has developed molecular imaging companion diagnostic tools for all of its therapeutic product candidates. The companion diagnostic agent attaches a molecular imaging agent to the same drug guidance system used for the therapeutic drug. The companion diagnostic provides a full-body, real-time image that can be used to determine whether the guidance system is targeting the diseased cells.
These powerful companion diagnostics are being used in all of our trials to identify the most appropriate patient population for clinical testing.
The diagnostic images below were obtained following administration of our folate-receptor targeted imaging agent EC20-Tc99m. The patient on the left shows no targeting to tumor (negative profile). The patient on the right shows targeting to tumors (positive profile).


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